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KMID : 0387820140210020177
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Clinical Pediatric Hematology-Oncology
2014 Volume.21 No. 2 p.177 ~ p.180
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Mucoepidermoid Carcinoma on Submandibular Salivary Gland as a Second Malignant Neoplasm after Treatment of Yolk Sac Tumor
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Keum Hyun-Sup
Kang Jung-In
Yoo Eun-Sun
Park Hee-Jung
Lee Sun-Wha
Ryu Kyung-Ha
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Abstract
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Malignant salivary gland tumors only represent 0.08% of all childhood tumors and mu-coepidermoid carcinoma (MEC) is the most common histologic type. Although there are many reports describing second malignant neoplasm (SMN) in patients treated for child-hood cancer, salivary gland tumors rarely appears. In Korea, there has been no report about MEC that developed in children as a SMN. We report a MEC in a 4 years and 8 months old female child that developed after completing treatment for yolk sac tumor of lower abdomen. The primary tumor presented with metastasis at the time of diagnosis, and therefore, the child underwent high-dose chemotherapy with autologous peripheral blood stem cell transplantation along with surgery and radiotherapy. Three years and five months after completing treatment, MEC developed in her submandibular gland. She was treated with surgery and radiotherapy and is in disease free state for 5 months at the time of this writing.
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KEYWORD
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Second malignant neoplasm, Mucoepidermoid carcinoma
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